Abnormal Laboratory Results: Creatinine clearance and the assessment of renal function
نویسندگان
چکیده
منابع مشابه
The assessment of glomerular function: creatinine clearance or plasma creatinine?
Plasma creatinine concentration is superior to creatinine clearance for the detection of abnormal glomerular function, of changes of glomerular function in patients with chronic renal disease. Creatinine clearance should be abandoned as the routine assessment of glomerular function.
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We compared creatinine clearances determined by enzymatic (Kodak Ektachem 700 single-slide, Boehringer Mannheim creatinine PAP) and nonenzymatic (Jaffé, HPLC) methods with glomerular filtration rate measured by inulin clearance in patients with varying degrees of renal function. The Kodak enzymatic assay gave values for creatinine 2 to 3 mg/L higher than the other methods. This resulted in sign...
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Measurement of creatinine clearance (CCr) has long been a problem in sick patients, largely because of the need to collect a carefully timed urine specimen to determine it. However, a number of years ago, several methods were developed to estimate CCr without a urine specimen [1-4]. However, all these approaches only considered the situation where serum creatinine was stable. Because of this, a...
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We compared creatinine concentrations in serum and urine and creatinine clearances determined by two Jaffé (Beckman's "Astra," Boehringer Mannheim Diagnostics) and two enzymatic (Kodak, Boehringer Mannheim Diagnostics) methods. Serum creatinine and creatinine clearances determined by each method were also compared with the glomerular filtration rate as measured with use of sodium [125I]iothalam...
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To determine the validity of endogenous creatinine clearance as a measure of glomerular filtration rate in patients with renal disease 308 simultaneous determinations of inulin clearance and endogenous creatinine clearance were reviewed and analysed. The ratio of creatinine clearance/inulin clearance increased progressively with the decline in inulin clearance, while the finding of a normal end...
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ژورنال
عنوان ژورنال: Australian Prescriber
سال: 2001
ISSN: 0312-8008,1839-3942
DOI: 10.18773/austprescr.2001.009